MassIVE: Mass Spectrometry Interactive Virtual Environment

MassIVE is a worldwide mass spectrometry data repository integrated into a flexible, scalable, user-friendly framework offering a diverse set of data analysis algorithms.

MassIVE

Software Tools & Datasets

MassIVE Datasets: Available datasets
MassIVE Submissions: Submit a new dataset

Key Publications

Interkingdom metabolic transformations captured by microbial imaging mass spectrometry. Moree WJ, Phelan VV, Wu CH, Bandeira N, Cornett DS, Duggan BM, Dorrestein PC. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13811-6. doi: 10.1073/pnas.1206855109.
The generating function approach for peptide identification in spectral networks Guthals A., Christina B. Bandeira N. Research in Computational Molecular Biology, Lecture Notes in Computer Science; (8394) 85-99
Protein identification by spectral networks analysis. Bandeira N. Methods Mol Biol. 2011;694:151-68. doi: 10.1007/978-1-60761-977-2_11.
Mass spectral molecular networking of living microbial colonies. Watrous J, Roach P, Alexandrov T, Heath BS, Yang JY, Kersten RD, van der Voort M, Pogliano K, Gross H, Raaijmakers JM, Moore BS, Laskin J, Bandeira N, Dorrestein PC. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):E1743-52. doi: 10.1073/pnas.1203689109. Epub 2012 May 14.
Shotgun protein sequencing with meta-contig assembly. Guthals A, Clauser KR, Bandeira N. Mol Cell Proteomics. 2012 Oct;11(10):1084-96.
Sequencing-grade de novo analysis of MS/MS triplets (CID/HCD/ETD) from overlapping peptides. Guthals A, Clauser KR, Frank AM, Bandeira N. J Proteome Res. 2013 Jun 7;12(6):2846-57.
View All CCMS Publictions

The public availability of mass spectrometry data is increasingly recognized as indispensable for the future of computational mass spectrometry and, consequently, for the collective ability of the proteomics community to progress towards efficiently reutilizing the billions of spectra already acquired and the many millions more being generated on a daily basis. But despite the pioneering efforts of the Tranche/ProteomeCommons system and the essential integration services under development by the ProteomeXchange consortium, there is still a pressing need for data repositories designed not only for reliable sharing of primary data but also offering user-friendly tools for advanced data analysis and visualization. MassIVE is a new mass spectrometry data repository designed to store, browse, redistribute, re-analyze and integrate all publicly available mass spectrometry data.

Since its inception, MassIVE has imported multiple Terabytes of mass spectrometry data in over 6,000 datasets from the now-extinct Tranche repository which are now available as MassIVE datasets and can be searched using the original Tranche hash strings. In addition, new datasets submissions to MassIVE already more than doubled the volume of data recovered from Tranche and continue to increase the volume and diversity of mass spectrometry data available to the proteomics community.