Principal Investigator

Pavel Pevzner

It is impossible to imagine modern biology without computational ideas developed by bioinformatics pioneers in the last two decades. Today, computational molecular biology remains a wild frontier with still unexplored boundaries.

Bioinformatics is often defined as applications of computers in biology. We respectfully disagree: reducing bioinformatics to “applications of computers in biology” diminishes the rich intellectual content of bioinformatics.

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Pavel Pevzner

Contact Info

Email Address: ppevzner@ucsd.edu
Phone Number: (858) 524-8666
Fax: (858) 524-8666
Location: Department of Computer Science & Engineering
University of California, San Diego
9500 Gilman Drive, EBU3b 4236
La Jolla, CA 92093-0404

Key Publications

Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage Grindberg RV, Ishoey T, Brinza D, Esquenazi E, Coates RC, Liu WT, Gerwick L, Dorrestein PC, Pevzner P, Lasken R, Gerwick WH. PLoS One. 2011 Apr 12;6(4):e18565. doi: 10.1371/journal.pone.0018565.
Interpreting top-down mass spectra using spectral alignment Frank AM, Pesavento JJ, Mizzen CA, Kelleher NL, Pevzner PA. Anal Chem. 2008 Apr 1;80(7):2499-505. doi: 10.1021/ac702324u. Epub 2008 Feb 27.
Top-down proteomics reveals a unique protein s-thiolation switch in the bacterial pathogen salmonella in response to infection-like conditions C. Ansong, S. Wu, M. Da, X. Liu, H. Brewer, L. Brooke, D. Kaiser, Nakayasu E.S., P.A. Cort, J.R.and Pevzner, R.D. Smith, F. Heffron, J.N. Adkins, and L. Pasa-Tolic. Proc Natl Acad Sci U S A, 110:10153--8, 2013.
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Research Interests

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I am interested in new approaches to teaching computational molecular biology at both undergraduate and graduate level:

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